Endocrine Abstracts

Objective: To determine the influence of metabolic disturbances associated with diabetes mellitus (DM) on the clinical manifestations of the diabetic neurogenic bladder (DNB).Patients and Methods: Analytical cross-sectional study comparing two groups of patients suffering from DM: G1 (n=159) with manifestations of DNB versus G2 (n=41) without signs of DNB.Results: G2 patients were younger than G1 patients (58±1...

Objective: To describe the etiological profile the outcomes of acute pancreatitis (AP) in patients with type 1 diabetes (T1DM).Patients and Methods: A retrospective descriptive study of 10 T1DM patients who presented at least one episode of AP during their follow-up.Results: The mean age at diagnosis of T1DM was 19.7±9.3 years, with a female predominance (60%). T1DM was frequently inaugurated by a cardinal syndrome (50%) or spon...

Background/Aims: Ketosis in patients with known Type 2 diabetes mellitus is overlooked due to atypical symptoms. Type 2 diabetes (DT2) is characterized by a longer period of asymptomatic hyperglycaemia than Type 1 diabetes(DT1). The objective of this study was to compare glycosylated haemoglobin (HbA1c) levels in ketoacidosis (DKA) occurring in known and newly diagnosed diabetes.Methods: This is a retrospective cross-sectional descriptive study concernin...

Background/aims: Although patients with diabetic ketoacidosis (DKA) are expected to have total body potassium depletion, measured levels may be normal or elevated due to extracellular shifts of potassiumsecondary to acidosis. We aimed to examine the prevalence of hypokalemia in patients with DKA at presentation and during the treatment.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrino...

Introduction: Anemia is defined by the World Health Organization as a hemoglobin concentration less than 120 g/l in women outside of pregnancy, and less than 130 g/l in men over 15 years of age. It is common in diabetics. It can be due to an autoimmune disease associated with type 1 diabetes, whereas the inflammatory cause is the primary cause in type 2 diabetes.Observation: This is a 75 year old patient, type 2 diabetic for 21 years on insulin analogues...

Introduction: Lipemic specimens could be a source of significant analytical errors. The aim of this study was to examine the effect of lipid removal using ultra-centrifugation of lipemic samples, on some routine biochemistry parameters.Observation: A 53-year-old man hospitalized in endocrinology department for treatment of severe hypertriglyceridemia (21.3 mmol/l). All the patient’s routine biochemical parameters were held on AU 680®...

Background and aim: Non-diabetic hypoglycemia is a rare entity that regroups several pathologies. Its exact diagnosis is mostly challenging. Endogenous hyperinsulinism is a curable cause that should be thoroughly screened. The objective of our study was to analyze the ethipathological aspects of hypoglycemia by endogenous hyperinsulinism.Patients and methods: We conducted a retrospective study at the Endocrinology department of Hedi Chaker University Hos...

Background and aim: Acromegaly is mostly due to a somatotropic adenoma. Regarding its insidious nature, this adenoma is often revealed at an invasive stage. This study aims to describe the radiological specificities of somatotropic adenomas at the time of diagnosisPatients and methods: We conducted a retrospective study at the Endocrinology department of Hedi Chaker University Hospital, Sfax, Tunisia. We involved 29 patients diagnosed with acromegaly, wh...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth, cardiometabolic disturbances and an increased neoplastic risk. This study aims to assess the tumorigenic potential of GH excessive secretion.Patients and Methods: We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth and cardiometabolic disturbances. This study aims to describe the ophthalmologic complications seen in acromegaly.Patients and Methods : We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker University Hospital, Sfax,...